IOCB Prague

Dmytro Yushchenko Group

Chemical Biology
Research Group
CHEM cluster

About our group

The research interests of our group are focused on the development of biochemical tools to study the biology of amyloidogenic proteins and lipid‐mediated cell signaling. We investigate the mechanisms of cytotoxicity of Parkinson's disease‐associated protein α‐synuclein and construct inhibitors of its fibrillization. We develop photocaged and photoswitchable molecules that permit spatio‐temporal control of protein and lipid activity in living cells as well as solvatochromic probes for sensing protein‐membrane interactions.